Issue: Vojnosanit Pregl 2017; Vol. 74 (No. 4)
Abdominal localization of unicentric form of Castleman disease − A case report
Authors:
Boško Milev, Borka Milev, Zoran Kostić, Darko Mirković, Nenad Perišić, Olga Tasić, Marija Elez, Aleksandar Radunović, Milan Jovanović, Predrag Marić, Sanja Daišević, Rade Prelević, Maja Vulović
Introduction. Castleman disease is a rare disease of the unknownetiology, occuring in two clinical forms: unicentric or multicentric.
It is characterized by the hyperplasia of lymph glands. In literature
the four pathohistological forms were described: hyaline vascular
type, plasma cell type, mixed type and a recently recognized
plasmablastic type. The most frequent changes are localized in the
mediastinum, while the abdominal localization is with significatly
rare occurrence, and that was the motive for presentation of this
case. Case report. In a 41-year old male magnetic resonance (MR)
enterography showed a change in the ileocecal area without the
presence of subjective symptoms of digestive tract and without
loss of body mass. Due to the suspicion of stromal tumor, surgical
intervention was indicated. Pathohistological findings showed
Castleman lymphadenopathia reactiva mesenterii (plasma cell type) which
was in the unicentric form. There were present only anaemia and
the increased value of sedimentation from the laboratory analyses.
Conclusion. Abdominal localization of unicentric plasma cell
form occurs rarely and the surgical method of treatment presents
the golden standard as it was shown in the presented case.
