Issue: Vojnosanit Pregl 2017; Vol. 74 (No. 4)

In vivo methodology in behavioural pharmacology – Where are we now?

Authors:
Janko Samardžić, Milica Borovčanin, Slavica Djukić Dejanović, Jasna Jančić, Miloš Djurić, Dragan I. Obradović

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shaft are common, however, ipsilateral neck and shaft humerus
fracture is a rare phenomenon. This combination injury
is challenging for orthopaedic surgeons because of its
complex treatment options at present. The purpose of this
study was to review a series of ipsilateral humeral neck and
shaft fractures to study the fracture pattern, complications
and treatment outcomes of each treatment options used.
Methods. A total of six patients (four female and two male)
with the average age of 42.8 years (range: 36–49 years) was
collected and reviewed retrospectively. Two of them were
treated with double plates and four with antegrade intramedullary
nail. According to the Neer’s classification, all proximal
fractures were two-part surgical neck fractures. All
humeral shaft fractures were located at the middle of one
third. Five fractures were simple transverse (A3), one fragmented
wedge fracture (B3). One patient had associated radial
nerve palsy. Results. All surgical neck fractures except
one united uneventfully in the average time span of 8.7
weeks. Four humeral shaft fractures healed in near anatomic
alignment. The remaining two patients had the nonunion
with no radiological signs of fracture healing. The average
University of California, Los Angeles End-Results (UCLA)
score was 23.1. On the contrary, the average American
Shoulder and Elbow Surgeon's (ASES) score was 73.3. The
patients treated with antegrade intramedullary nails presented
70.5 points. The ASES scores were 79 in the double
plates group. Conclusions. Ipsilateral humeral shaft and
neck fracture is extremely rare. Both antegrade intramedullar
nailing and double plates result in healing of fractures.
However the risk of complication is lower in the double
plating group.