Issue: Vojnosanit Pregl 2017; Vol. 74 (No. 3)

Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning – A case report

Authors:
Gordana Vuković Ercegović, Nataša Perković Vukčević, Snežana Djordjević, Zoran Šegrt, Olivera Potrebić, Snežana R. Janković, Jasmina Jović Stošić, Nadica Marinković

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Introduction. During the last few years, intravenous lipid
emulsions have been effectively used in treatment of acute
poisonings with lipophilic substances, including verapamil.
Case report. A 37-year-old women presented 1 hour after
ingestion of 2.8 g verapamil with hypotension and complete
heart block. Because of the applied standard therapy failure
and further patients impairment, Intralipid® 20% was used.
Sinus rhythm was restored, arterial blood pressure increased
and verapamile concentrations, both total and free decreased.
Conclusion. Intravenous lipid emulsion can be
important in treatment of severe acute intoxication and cardiotoxicity
caused by verapamil