Issue: Vojnosanit Pregl 2017; Vol. 74 (No. 2)
The importance of impulse oscillometry in bronchial provocation testing in confirming the diagnosis of asthma in male army recruits
Authors:
Dragan Koruga, Kristina Tot Vereš, Goran Plavec, Olivera Lončarević
Background/Aim. Impulse oscillometry (IOS) is a techniquevalid for measuring the lung function in obstructive lung diseases
and bronchial provocation tests. However, no consensus
exists for its use. The aim of the study was to assess impulse
oscillometry sensitivity for detection of early airways changes
during bronchial provocation testing and to compare with
changes obtained with spirometry and bodyplethysmography in
male army recruits. Methods. Male military recruits were submitted
to bronchial provocation test with histamine by the aerosol
provocation system. Out of 52 male military recruits subjected
to attempts to make the diagnosis of asthma the study
included 31 subjects with fall of forced expiratory volume in
one second (FEV1) above 20%. The changes of impulse
oscillometry were measured one step before and after provocation
dose (PD) of histamine and compared with the changes of
bodyplethysmography and spirometry. Results. The average
age of male army recruits was 23.3 year. After bronchoprovocation
there was an average increase of the total resistance at 5
Hz (R5) by 66.6%, resonant frequency (Fres) by 102.2%, Goldman
index (AX) by 912.1%, the arway resistance (Raw) by
121.5%, and a decrease in reactance at 5 Hz (X5) by 132.1%
and FEV1 by 25.6%. One step before the last inhaled of PD20
there was an average increase of 26.7% in R5, 24.1% in Fres,
85.3% in AX, 11.9% in Raw and a decrease in X5 by 26.9%
and FEV1 by 4.3%. A correlation between impulse
oscillometry and bodyplethysmography parameters was obtained.
Conclusion. This paper demonstrates a sufficient
sensitivity of impulse oscillometry to detect changes in airways,
so it may play a complementary role in the diagnosis of asthma
in male military recruits.
