Issue: Vojnosanit Pregl 2016; Vol. 73 (No. 12)
Community-acquired urinary tract infections: causative agents and their resistance to antimicrobial drugs
Authors:
Zorana Djordjević, Marko Folić, Slobodan Janković
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Background/Aim. Urinary tract infections (UTIs) are among the most common infections in outpatients. The aim of this study was to define the causative agents of urinary tract infections and their resistance to antimicrobial drugs in the urban area of central Serbia, as well as to evaluate even-tual differences associated with age and gender of the pa-tients. Methods. This retrospective study analysed data taken from routine, consecutively collected urine cultures of outpa-tients with symptomatic UTIs, collected from the Depart-ment of Microbiology, Institute of Public Health in Kragu-jevac, Serbia, from January 2009 to December 2013. Results. There were 71,905 urine cultures, and 24,713 (34.37%) of them were positive for bacterial pathogens. The most com-mon pathogen was Escherichia coli (E. coli) (56.56%), followed by Klebsiella spp. (16.20%), Proteus spp. (14.68%), Enterococcus spp. (5.29%) and Pseudomonas aeruginosa (3.74%). E. coli and Enterococcus spp. isolation rates were lower in males ≥ 60 years old (23.71% and 4.87%, respectively), while Klebsiella spp. was more prevalent in this group (32.06%). The most common causative agents isolated from 15–29 years old male patients were Enterococcus spp. and Pseudomonas aeruginosa (13.28% each). Among women, the isolation rate of E.coli was high in all age groups (around 70%). Proteus spp. was frequently iso-lated from females ≤ 14 years old (13.27%), while Klebsiella spp. was the most frequent in the oldest age female group (10.99%). Conclusion. Choice of antibiotics for treatment of UTIs should be governed not only by the local resistance pat-terns, but also by gender and age of patients.